The effect of change in body mass index on volumetric measures of mammographic density.

ABSTRACT:

Background

Understanding how changes in body mass index (BMI) relate to changes in mammographic density is necessary to evaluate adjustment for BMI gain/loss in studies of change in density and breast cancer risk. Increase in BMI has been associated with a decrease in percent density, but the effect on change in absolute dense area or volume is unclear.

Methods

We examined the association between change in BMI and change in volumetric breast density among 24,556 women in the San Francisco Mammography Registry from 2007 to 2013. Height and weight were self-reported at the time of mammography. Breast density was assessed using single x-ray absorptiometry measurements. Cross-sectional and longitudinal associations between BMI and dense volume (DV), non-dense volume (NDV), and p

SUBMITTER: Hart V 

PROVIDER: S-EPMC4633314 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature