Rewarding, stimulant, and sedative alcohol responses and relationship to future binge drinking.

ABSTRACT:

Context

Excessive consumption of alcohol is a major problem in the United States and abroad. Despite many years of study, it is unclear why some individuals drink alcohol excessively while others do not. It has been postulated that either lower or greater acute responses to alcohol, or both, depending on the limb of the breath alcohol concentration curve, contribute to propensity for alcohol misuse.

Objective

To prospectively assess the relationship of acute alcohol responses to future binge drinking.

Design

Within-subject, double-blind, placebo-controlled, multidose laboratory alcohol challenge study with intensive follow-up. Each participant completed 3 randomized sessions examining responses to a high (0.8 g/kg) and low (0.4 g/kg) alcohol dose and placebo, followed

SUBMITTER: King AC 

PROVIDER: S-EPMC4633413 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature