Strategies and Advancements in Harnessing the Immune System for Gastric Cancer Immunotherapy.

ABSTRACT: In cancer biology, cells and molecules that form the fundamental components of the tumor microenvironment play a major role in tumor initiation, and progression as well as responses to therapy. Therapeutic approaches that would enable and harness the immune system to target tumor cells mark the future of anticancer therapy as it could induce an immunological memory specific to the tumor type and further enhance tumor regression and relapse-free survival in cancer patients. Gastric cancer is one of the leading causes of cancer-related mortalities that has a modest survival benefit from existing treatment options. The advent of immunotherapy presents us with new approaches in gastric cancer treatment where adaptive cell therapies, cancer vaccines, and antibody therapies have all been used wi

SUBMITTER: Subhash VV 

PROVIDER: S-EPMC4633567 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature