HIV Transmission Networks in the San Diego-Tijuana Border Region.

ABSTRACT:

Background

HIV sequence data can be used to reconstruct local transmission networks. Along international borders, like the San Diego-Tijuana region, understanding the dynamics of HIV transmission across reported risks, racial/ethnic groups, and geography can help direct effective prevention efforts on both sides of the border.

Methods

We gathered sociodemographic, geographic, clinical, and viral sequence data from HIV infected individuals participating in ten studies in the San Diego-Tijuana border region. Phylogenetic and network analysis was performed to infer putative relationships between HIV sequences. Correlates of identified clusters were evaluated and spatiotemporal relationships were explored using Bayesian phylogeographic analysis.

Findings

After quality fil

SUBMITTER: Mehta SR 

PROVIDER: S-EPMC4634195 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature