Respiratory syncytial virus epidemic periods in an equatorial city of Brazil.

ABSTRACT:

Background

Characterization of the human respiratory syncytial virus (HRSV) season at the local level has important implications for appropriate decisions on the time period for administration of specific prophylaxis.

Objectives

(1) To describe five consecutive epidemic periods of HRSV in an equatorial city of Brazil and (2) to show preliminary data on genomic diversity of circulating HRSV.

Patients/methods

Nasopharyngeal aspirates of 2885 children attending the emergency room and wards of a public hospital were collected and screened by indirect immunofluorescence for HRSV infections during five consecutive years (from January 2004 to December 2008). In addition, the genetic and antigenic variability of the HRSV strains isolated was evaluated by partial nucleotide se

SUBMITTER: Moura FE 

PROVIDER: S-EPMC4634240 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature