Regional variation in mortality impact of the 2009 A(H1N1) influenza pandemic in China.

ABSTRACT:

Background

Laboratory-confirmed deaths grossly underestimate influenza mortality burden, so that reliable burden estimates are derived from indirect statistical studies, which are scarce in low- and middle-income settings.

Objectives

Here, we used statistical excess mortality models to estimate the burden of seasonal and pandemic influenza in China.

Methods

We modeled data from a nationally representative population-based death registration system, combined with influenza virological surveillance data, to estimate influenza-associated excess mortality for the 2004-2005 through 2009-2010 seasons, by age and region.

Results

The A(H1N1) pandemic was associated with 11·4-12·1 excess respiratory and circulatory (R&C) deaths per 100,000 population in rural sites of n

SUBMITTER: Yu H 

PROVIDER: S-EPMC4634298 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature