Circulating Unsaturated Fatty Acids Delineate the Metabolic Status of Obese Individuals.

ABSTRACT:

Background

Obesity is not a homogeneous condition across individuals since about 25-40% of obese individuals can maintain healthy status with no apparent signs of metabolic complications. The simple anthropometric measure of body mass index does not always reflect the biological effects of excessive body fat on health, thus additional molecular characterizations of obese phenotypes are needed to assess the risk of developing subsequent metabolic conditions at an individual level.

Methods

To better understand the associations of free fatty acids (FFAs) with metabolic phenotypes of obesity, we applied a targeted metabolomics approach to measure 40 serum FFAs from 452 individuals who participated in four independent studies, using an ultra-performance liquid chromatograph coupl

SUBMITTER: Ni Y 

PROVIDER: S-EPMC4634820 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature