Ontology highlight
ABSTRACT:
SUBMITTER: Koharudin LM
PROVIDER: S-EPMC4635050 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Koharudin Leonardus M I LM Debiec Karl T KT Gronenborn Angela M AM
Structure (London, England : 1993) 20151009 11
MGG_03307 is a lectin isolated from Magnaporte oryzae, a fungus that causes devastating rice blast disease. Its function is associated with protecting M. oryzae from the host immune response in plants. To provide the structural basis of how MGG_03307 protects the fungus, crystal structures of its CVNH-LysM module were determined in the absence and presence of GlcNAc-containing cell wall chitin constituents, which can act as pathogen-associated molecular patterns. Our structures revealed that gly ...[more]