A J-shaped relationship between caloric intake and survival in critically ill patients.

ABSTRACT:

Background

There is much controversy around the optimal caloric intake in intensive care unit (ICU) patients, based on the diverging results of prospective studies. Therefore, we assessed the presence of an association between caloric intake and outcome in a large cohort included in the Glucontrol study.

Methods

Patients (n = 1004) were divided into four quartiles (q1-q4) according to the daily caloric intake (n = 251/quartile). ICU, hospital and 28-day mortality and the length of stay (LOS) in ICU and in the hospital were compared between each quartile, before and after adjustment in case of differences in baseline characteristics.

Results

Caloric intake averaged 0.5 ± 0.6 (q1), 3.0 ± 0.7 (q2), 13.4 ± 5.1 (q3) and 32.4 ± 8.5 (q4) kcal/kg/day (p < 0.001 between quarti

SUBMITTER: Crosara IC 

PROVIDER: S-EPMC4635112 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature