Alcohol consumption and the risk of Barrett's esophagus: a comprehensive meta-analysis.

ABSTRACT: Several studies have been proposed to investigate the association between alcohol consumption and risk of Barrett's esophagus (BE), but as of yet, no quantitative summary of the literature to clarify the relationship between them. In our study, twenty eligible cohort studies involving 42925 participants were identified. Combined relative risk (RR) ratios for the highest versus lowest alcohol consumption levels were calculated. The alcohol dose-response analysis was performed to investigate the association between the increment consumption of 10 g/d alcohol and the risk of developing BE. Subgroup analyses were used to examine heterogeneity across the studies. A combined RR of 0.98 (0.62-1.34) was found when comparing highest vs. lowest alcohol consumption levels for BE. An inverse associati

SUBMITTER: Ren LL 

PROVIDER: S-EPMC4635354 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature