Future Research Prioritization: Implantable Cardioverter-Defibrillator Therapy in Older Patients.

ABSTRACT:

Background

Although the implantable cardioverter-defibrillator (ICD) is highly effective therapy for preventing sudden cardiac death, there is considerable uncertainty about its benefits and harms in older patients, especially in the presence of factors, other than old age, that increase the risk of death.

Objective

To develop a prioritized research agenda for the Patient-Centered Outcomes Research Institute as informed by a diverse group of stakeholders on the use and outcomes of the ICD in older patients.

Design

The existing literature was reviewed to identify evidence gaps, which were then refined by engaged stakeholders. Using a forced-ranking prioritization method, the stakeholders ranked evidence gaps by importance. For the highest-ranked evidence gaps, relevant

SUBMITTER: Al-Khatib SM 

PROVIDER: S-EPMC4636565 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature