Intake of polyunsaturated fat in relation to mortality among statin users and non-users in the Southern Community Cohort Study.

ABSTRACT:

Background and aims

Consumption of polyunsaturated fatty acids (PUFA), especially the n3-series, may protect against cardiovascular disease (CVD), but recent randomized studies have failed to demonstrate these benefits. One of the prevailing hypotheses is that PUFA intake may not confer benefits beyond those provided by statins, but studies comparing statin users to non-users with regard to effects of PUFA are lacking.

Methods and results

Black and white men and women (n = 69,559) in the Southern Community Cohort Study were studied. Cox regression models adjusting for age, sex, race, BMI, recruitment site, education, income, smoking, diabetes, and dietary variables were used.

Results

At baseline the mean ± SD age was 52 ± 9 years, 60% of participants were women, 54% h

SUBMITTER: Kiage JN 

PROVIDER: S-EPMC4637133 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature