The genetic regulatory network centered on Pto-Wuschela and its targets involved in wood formation revealed by association studies.

ABSTRACT: Transcription factors (TFs) regulate gene expression and can strongly affect phenotypes. However, few studies have examined TF variants and TF interactions with their targets in plants. Here, we used genetic association in 435 unrelated individuals of Populus tomentosa to explore the variants in Pto-Wuschela and its targets to decipher the genetic regulatory network of Pto-Wuschela. Our bioinformatics and co-expression analysis identified 53 genes with the motif TCACGTGA as putative targets of Pto-Wuschela. Single-marker association analysis showed that Pto-Wuschela was associated with wood properties, which is in agreement with the observation that it has higher expression in stem vascular tissues in Populus. Also, SNPs in the 53 targets were associated with growth or wood properties unde

SUBMITTER: Yang X 

PROVIDER: S-EPMC4637887 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature