Dual-emissive Polymer Dots for Rapid Detection of Fluoride in Pure Water and Biological Systems with Improved Reliability and Accuracy.

ABSTRACT: It is of paramount importance to develop new probes that can selectively, sensitively, accurately and rapidly detect fluoride in aqueous media and biological systems, because F(-) is found to be closely related to many health and environmental concerns. Herein, a dual-emissive conjugated polyelectrolyte P1 containing phosphorescent iridium(III) complex was designed and synthesized, which can form ultrasmall polymer dots (Pdots) in aqueous media. The F(-)-responsive tert-butyldiphenylsilyl moiety was introduced into iridium(III) complex as the signaling unit for sensing F(-) with the quenched phosphorescence. Thus, the dual-emissive Pdots can rapidly and accurately detect F(-) in aqueous media and live cells as a ratiometric probe by measuring the change in the ratio of the F(-)-sensitive r

SUBMITTER: Zhao Q 

PROVIDER: S-EPMC4639760 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature