Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization.

ABSTRACT:

Background

Fertilization is a key physiological process for the preservation of the species. Consequently, different mechanisms affecting the sperm and the oocyte have been developed to ensure a successful fertilization. Thus, sperm acrosome reaction is necessary for the egg coat penetration and sperm-oolema fusion. Several molecules are able to induce the sperm acrosome reaction; however, this process should be produced coordinately in time and in the space to allow the success of fertilization between gametes. The goal of this study was to analyze the metabolites secreted by cumulus-oocyte-complex (COC) to find out new components that could contribute to the induction of the human sperm acrosome reaction and other physiological processes at the time of gamete interaction and fert

SUBMITTER: Gomez-Torres MJ 

PROVIDER: S-EPMC4640411 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature