A Diversity of Conserved and Novel Ovarian MicroRNAs in the Speckled Wood (Pararge aegeria).

ABSTRACT: microRNAs (miRNAs) are important regulators of animal development and other processes, and impart robustness to living systems through post-transcriptional regulation of specific mRNA transcripts. It is postulated that newly emergent miRNAs are generally expressed at low levels and with spatiotemporally restricted expression domains, thus minimising effects of spurious targeting on animal transcriptomes. Here we present ovarian miRNA transcriptome data for two geographically distinct populations of the Speckled Wood butterfly (Pararge aegeria). A total of 74 miRNAs were identified, including 11 newly discovered and evolutionarily-young miRNAs, bringing the total of miRNA genes known from P. aegeria up to 150. We find a positive correlation between miRNA age and expression level. A common s

SUBMITTER: Quah S 

PROVIDER: S-EPMC4640560 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature