Serum amyloid a gene polymorphism and its association with lipid profile in Saudi females with osteoporosis.

ABSTRACT:

Background and objective

Osteoporosis can be defined as a systemic skeletal disease characterized by low bone mass and micro architectural decline of bone tissue. Serum amyloid A (SAA) is a family of protein that increases up to 1,000-fold in blood during inflammation. In this study, we aimed to study the relationship between SAA1 gene polymorphism (rs12218) and lipid profile and osteoporosis.

Methods

The study was performed on the female students of Taibah University in Al Medina, KSA during June 2014 to April 2015. According to BMD; osteoporosis group (138 students) and control group (128 students). All groups were subjected to; BMI, BMD, calcium, phosphorus, creatinine, lipid profile and SAA. Polymerase chain reaction and Real Time were done to determine the distribution

SUBMITTER: Abdu-Allah AM 

PROVIDER: S-EPMC4641268 | biostudies-literature | 2015 Sep-Oct

REPOSITORIES: biostudies-literature