A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass.

ABSTRACT:

Background

Gastric bypass has profound effects on glycemic control in adults with type 2 diabetes mellitus. The goal of this study was to examine the long-term rates and clinical predictors of diabetes remission and relapse among patients undergoing gastric bypass.

Methods

We conducted a retrospective cohort study of adults with uncontrolled or medication-controlled type 2 diabetes who underwent gastric bypass from 1995 to 2008 in three integrated health care delivery systems in the USA. Remission and relapse events were defined by diabetes medication use and clinical laboratory measures of glycemic control. We identified 4,434 adults with uncontrolled or medication-controlled type 2 diabetes who had gastric bypass.

Results

Overall, 68.2 % (95 % confidence interval [C

SUBMITTER: Arterburn DE 

PROVIDER: S-EPMC4641311 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature