Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery--development and validation of a risk score and effect of acute kidney injury on survival: observational cohort study.

ABSTRACT:

Study question

What is the predicted risk of acute kidney injury after orthopaedic surgery and does it affect short term and long term survival?

Methods

The cohort comprised adults resident in the National Health Service Tayside region of Scotland who underwent orthopaedic surgery from 1 January 2005 to 31 December 2011. The model was developed in 6220 patients (two hospitals) and externally validated in 4395 patients from a third hospital. Several preoperative variables were selected for candidate predictors, based on literature, clinical expertise, and availability in the orthopaedic surgery setting. The main outcomes were the development of any severity of acute kidney injury (stages 1-3) within the first postoperative week, and 90 day, one year, and longer term survival.

SUBMITTER: Bell S 

PROVIDER: S-EPMC4641433 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature