Network Events on Multiple Space and Time Scales in Cultured Neural Networks and in a Stochastic Rate Model.

ABSTRACT: Cortical networks, in-vitro as well as in-vivo, can spontaneously generate a variety of collective dynamical events such as network spikes, UP and DOWN states, global oscillations, and avalanches. Though each of them has been variously recognized in previous works as expression of the excitability of the cortical tissue and the associated nonlinear dynamics, a unified picture of the determinant factors (dynamical and architectural) is desirable and not yet available. Progress has also been partially hindered by the use of a variety of statistical measures to define the network events of interest. We propose here a common probabilistic definition of network events that, applied to the firing activity of cultured neural networks, highlights the co-occurrence of network spikes, power-law dist

SUBMITTER: Gigante G 

PROVIDER: S-EPMC4641680 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature