ISRAP - a one-touch research tool for rapid profiling of small RNA-seq data.

ABSTRACT: Small non-coding RNAs have been significantly recognized as the key modulators in many biological processes, and are emerging as promising biomarkers for several diseases. These RNA species are transcribed in cells and can be packaged in extracellular vesicles, which are small vesicles released from many biotypes, and are involved in intercellular communication. Currently, the advent of next-generation sequencing (NGS) technology for high-throughput profiling has further advanced the biological insights of non-coding RNA on a genome-wide scale and has become the preferred approach for the discovery and quantification of non-coding RNA species. Despite the routine practice of NGS, the processing of large data sets poses difficulty for analysis before conducting downstream experiments. Often

SUBMITTER: Quek C 

PROVIDER: S-EPMC4641893 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature