A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins.

ABSTRACT:

Background

Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signaling molecules as well as their better known roles as antibiotics. To date, close to five hundred bacteriocins have been identified and classified. Recent discoveries have shown that bacteriocins are highly diverse and widely distributed among bacterial species. Given the heterogeneity of bacteriocin compounds, many tools struggle with identifying novel bacteriocins due to their vast sequence and structural diversity. Many bacteriocins undergo post-translational processing or modifications necessary for the biosynthesis of the final mature form. Enzymatic modification of bacteriocins as well as their export is achieved by proteins whose

SUBMITTER: Morton JT 

PROVIDER: S-EPMC4642626 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature