Randomized Trial of Reduced-Nicotine Standards for Cigarettes.

ABSTRACT:

Background

The Food and Drug Administration can set standards that reduce the nicotine content of cigarettes.

Methods

We conducted a double-blind, parallel, randomized clinical trial between June 2013 and July 2014 at 10 sites. Eligibility criteria included an age of 18 years or older, smoking of five or more cigarettes per day, and no current interest in quitting smoking. Participants were randomly assigned to smoke for 6 weeks either their usual brand of cigarettes or one of six types of investigational cigarettes, provided free. The investigational cigarettes had nicotine content ranging from 15.8 mg per gram of tobacco (typical of commercial brands) to 0.4 mg per gram. The primary outcome was the number of cigarettes smoked per day during week 6.

Results

A total o

SUBMITTER: Donny EC 

PROVIDER: S-EPMC4642683 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature