Identification of putative adhesins of Actinobacillus suis and their homologues in other members of the family Pasteurellaceae.

ABSTRACT:

Background

Actinobacillus suis disease has been reported in a wide range of vertebrate species, but is most commonly found in swine. A. suis is a commensal of the tonsils of the soft palate of swine, but in the presence of unknown stimuli it can invade the bloodstream, causing septicaemia and sequelae such as meningitis, arthritis, and death. It is genotypically and phenotypically similar to A. pleuropneumoniae, the causative agent of pleuropneumonia, and to other members of the family Pasteurellaceae that colonise tonsils. At present, very little is known about the genes involved in attachment, colonisation, and invasion by A. suis (or related members of the tonsil microbiota).

Results

Bioinformatic analyses of the A. suis H91-0380 genome were done using BASys and blastx in

SUBMITTER: Bujold AR 

PROVIDER: S-EPMC4644294 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature