Neonatal Glycemia and Neurodevelopmental Outcomes at 2 Years.

ABSTRACT:

Background

Neonatal hypoglycemia is common and can cause neurologic impairment, but evidence supporting thresholds for intervention is limited.

Methods

We performed a prospective cohort study involving 528 neonates with a gestational age of at least 35 weeks who were considered to be at risk for hypoglycemia; all were treated to maintain a blood glucose concentration of at least 47 mg per deciliter (2.6 mmol per liter). We intermittently measured blood glucose for up to 7 days. We continuously monitored interstitial glucose concentrations, which were masked to clinical staff. Assessment at 2 years included Bayley Scales of Infant Development III and tests of executive and visual function.

Results

Of 614 children, 528 were eligible, and 404 (77% of eligible children) w

SUBMITTER: McKinlay CJ 

PROVIDER: S-EPMC4646166 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature