Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow.

ABSTRACT: Continuous monitoring of variations in blood flow is vital in assessing the status of microvascular and macrovascular beds for a wide range of clinical and research scenarios. Although a variety of techniques exist, most require complete immobilization of the subject, thereby limiting their utility to hospital or clinical settings. Those that can be rendered in wearable formats suffer from limited accuracy, motion artifacts, and other shortcomings that follow from an inability to achieve intimate, noninvasive mechanical linkage of sensors with the surface of the skin. We introduce an ultrathin, soft, skin-conforming sensor technology that offers advanced capabilities in continuous and precise blood flow mapping. Systematic work establishes a set of experimental procedures and theoretical m

SUBMITTER: Webb RC 

PROVIDER: S-EPMC4646823 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature