Deciphering the signaling mechanisms of the plant cell wall degradation machinery in Aspergillus oryzae.

ABSTRACT:

Background

The gene expression and secretion of fungal lignocellulolytic enzymes are tightly controlled at the transcription level using independent mechanisms to respond to distinct inducers from plant biomass. An advanced systems-level understanding of transcriptional regulatory networks is required to rationally engineer filamentous fungi for more efficient bioconversion of different types of biomass.

Results

In this study we focused on ten chemically defined inducers to drive expression of cellulases, hemicellulases and accessory enzymes in the model filamentous fungus Aspergillus oryzae and shed light on the complex network of transcriptional activators required. The chemical diversity analysis of the inducers, based on 186 chemical descriptors calculated from the struc

SUBMITTER: Udatha DB 

PROVIDER: S-EPMC4647334 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature