Transcriptome-wide functional characterization reveals novel relationships among differentially expressed transcripts in developing soybean embryos.

ABSTRACT:

Background

Transcriptomics reveals the existence of transcripts of different coding potential and strand orientation. Alternative splicing (AS) can yield proteins with altered number and types of functional domains, suggesting the global occurrence of transcriptional and post-transcriptional events. Many biological processes, including seed maturation and desiccation, are regulated post-transcriptionally (e.g., by AS), leading to the production of more than one coding or noncoding sense transcript from a single locus.

Results

We present an integrated computational framework to predict isoform-specific functions of plant transcripts. This framework includes a novel plant-specific weighted support vector machine classifier called CodeWise, which predicts the coding potential o

SUBMITTER: Aghamirzaie D 

PROVIDER: S-EPMC4647491 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature