Background risk of breast cancer influences the association between alcohol consumption and mammographic density.

ABSTRACT:

Background

Alcohol consumption has been suggested to increase risk of breast cancer through a mechanism that also increases mammographic density. Whether the association between alcohol consumption and mammographic density is modified by background breast cancer risk has, however, not been studied.

Methods

We conducted a population-based cross-sectional study of 53 060 Swedish women aged 40-74 years. Alcohol consumption was assessed using a web-based self-administered questionnaire. Mammographic density was measured using the fully-automated volumetric Volpara method. The Tyrer-Cuzick prediction model was used to estimate risk of developing breast cancer in the next 10 years. Linear regression models were used to evaluate the association between alcohol consumption and volum

SUBMITTER: Trinh T 

PROVIDER: S-EPMC4647543 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature