Population preference values for health states in relapsed or refractory B-precursor acute lymphoblastic leukemia in the United Kingdom.

ABSTRACT:

Background

To date, reliable and comprehensive health-related quality of life data for patients with relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL) have not been collected in clinical trials of the disease, and no utility studies have been published. The purpose of this study was to define and validate health states experienced by adults with relapsed/refractory B-precursor ALL, and to assign utility values to these health states using time-trade off methodology.

Methods

This study was conducted in the UK in three phases. In the first phase, five health state descriptions were developed based on a recent clinical trial. The second phase validated the health state descriptions with clinicians and patients with experience of relapsed/refractory B-precurs

SUBMITTER: Aristides M 

PROVIDER: S-EPMC4647711 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature