Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: An observational cohort study.

ABSTRACT:

Purpose

Patients with severe sepsis and septic shock are at high risk for development of pulmonary complications, including acute respiratory distress syndrome (ARDS). Serial lactate monitoring is a useful tool to gauge global tissue hypoxia in emergency department (ED) patients with sepsis. We hypothesized that patients undergoing serial lactate monitoring (SL) would demonstrate a decreased incidence of pulmonary complications.

Methods

This is a retrospective observational cohort study of adult severe sepsis and septic shock patients with elevated lactate presenting to a large academic ED. A total of 243 patients were assigned to SL (n=132) or no serial lactate monitoring (NL; n=111). The primary outcome was a composite of pulmonary complications: (1) ARDS development and (

SUBMITTER: Dettmer MR 

PROVIDER: S-EPMC4648355 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature