Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis.

ABSTRACT:

Aim

To study the safety of epidural anesthesia (EA), its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis (AP).

Methods

From 2005 to August 2010, patients with predicted severe AP [Ranson score ≥ 2, C-reactive protein > 100 or necrosis on computed tomography (CT)] were prospectively randomized to either a group receiving EA or a control group treated by patient controlled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale (VAS). Parameters for clinical severity such as length of hospital stay, use of antibiotics, admission to the intensive care unit, radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT

SUBMITTER: Sadowski SM 

PROVIDER: S-EPMC4649128 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature