KATZLDA: KATZ measure for the lncRNA-disease association prediction.

ABSTRACT: Accumulating experimental studies have demonstrated important associations between alterations and dysregulations of lncRNAs and the development and progression of various complex human diseases. Developing effective computational models to integrate vast amount of heterogeneous biological data for the identification of potential disease-lncRNA associations has become a hot topic in the fields of human complex diseases and lncRNAs, which could benefit lncRNA biomarker detection for disease diagnosis, treatment, and prevention. Considering the limitations in previous computational methods, the model of KATZ measure for LncRNA-Disease Association prediction (KATZLDA) was developed to uncover potential lncRNA-disease associations by integrating known lncRNA-disease associations, lncRNA expres

SUBMITTER: Chen X 

PROVIDER: S-EPMC4649494 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature