Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus.

ABSTRACT: The maize Ac/Ds transposon family was the first transposable element system identified and characterized by Barbara McClintock. Ac/Ds transposons belong to the hAT family of class II DNA transposons. We and others have shown that Ac/Ds elements can undergo a process of alternative transposition in which the Ac/Ds transposase acts on the termini of two separate, nearby transposons. Because these termini are present in different elements, alternative transposition can generate a variety of genome alterations such as inversions, duplications, deletions, and translocations. Moreover, Ac/Ds elements transpose preferentially into genic regions, suggesting that structural changes arising from alternative transposition may potentially generate chimeric genes at the rearrangement breakpoints. Here

SUBMITTER: Wang D 

PROVIDER: S-EPMC4649661 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature