MICCA: a complete and accurate software for taxonomic profiling of metagenomic data.

ABSTRACT: The introduction of high throughput sequencing technologies has triggered an increase of the number of studies in which the microbiota of environmental and human samples is characterized through the sequencing of selected marker genes. While experimental protocols have undergone a process of standardization that makes them accessible to a large community of scientist, standard and robust data analysis pipelines are still lacking. Here we introduce MICCA, a software pipeline for the processing of amplicon metagenomic datasets that efficiently combines quality filtering, clustering of Operational Taxonomic Units (OTUs), taxonomy assignment and phylogenetic tree inference. MICCA provides accurate results reaching a good compromise among modularity and usability. Moreover, we introduce a de-no

SUBMITTER: Albanese D 

PROVIDER: S-EPMC4649890 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature