Strategy and rationale for urine collection protocols employed in the NEPTUNE study.

ABSTRACT:

Background

Glomerular diseases are potentially fatal, requiring aggressive interventions and close monitoring. Urine is a readily-accessible body fluid enriched in molecular signatures from the kidney and therefore particularly suited for routine clinical analysis as well as development of non-invasive biomarkers for glomerular diseases.

Methods

The Nephrotic Syndrome Study Network (NEPTUNE; ClinicalTrials.gov Identifier NCT01209000) is a North American multicenter collaborative consortium established to develop a translational research infrastructure for nephrotic syndrome. This includes standardized urine collections across all participating centers for the purpose of discovering non-invasive biomarkers for patients with nephrotic syndrome due to minimal change disease, fo

SUBMITTER: Hogan MC 

PROVIDER: S-EPMC4650313 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature