Time course of the response to ACTH in pig: biological and transcriptomic study.

ABSTRACT:

Background

HPA axis plays a major role in physiological homeostasis. It is also involved in stress and adaptive response to the environment. In farm animals in general and specifically in pigs, breeding strategies have highly favored production traits such as lean growth rate, feed efficiency and prolificacy at the cost of robustness. On the hypothesis that the HPA axis could contribute to the trade-off between robustness and production traits, we have designed this experiment to explore individual variation in the biological response to the main stress hormone, cortisol, in pigs. We used ACTH injections to trigger production of cortisol in 120 juvenile Large White (LW) pigs from 28 litters and the kinetics of the response was measured with biological variables and whole blood gene

SUBMITTER: Sautron V 

PROVIDER: S-EPMC4650497 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature