RNA Pol II as a sensor of 5caC.

ABSTRACT: Cytosines in genomic DNA come in different flavors. A recent paper published in Nature reveals that an oxidized variety, 5-carboxylcytosine, is recognized by the elongating RNA polymerase, shedding light on the role of DNA oxidation in transcription regulation.

SUBMITTER: Xue JH 

PROVIDER: S-EPMC4650622 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature