Inherently stealthy and highly tumor-selective gold nanoraspberries for photothermal cancer therapy.

ABSTRACT: Owing to their unique optical properties such as large absorption and scattering cross section and large enhancement of electromagnetic field at the surface, plasmonic nanostructures have received extensive attention as a highly promising class of materials for nano-oncology. Most of the existing plasmonic nanostructures require extensive post-synthesis treatments and biofunctionalization routines to mitigate their cytotoxicity and/or make them tumor-specific. Here, we report one-pot synthesis of a novel class of plasmonic nanostructures, namely, gold nanoraspberries (GRBs) with tunable size and localized surface plasmon resonance by using a naturally abundant polysaccharide, chitosan, which acts as a template and capping agent. Significantly, the GRBs, which do not require any further bio

SUBMITTER: Gandra N 

PROVIDER: S-EPMC4650759 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature