Association between recent use of proton pump inhibitors and nontyphoid salmonellosis: a nested case-control study.

ABSTRACT:

Background

The association between proton pump inhibitors (PPIs) and nontyphoid salmonellosis (NTS) continues to be debated. The current study was designed to determine the association between use of oral PPIs and the diagnosis of NTS.

Methods

The Taiwan National Health Insurance Research Database from 2000 to 2010 was searched for cases of NTS, defined by the International Classification of Disease, Ninth revision, Clinical Modification. A nested case-control study in hospitalized population was conducted using 4 controls for each case patient (14 736 case patients and 58 944 controls), matched for age, month and year of entry, Charlson comorbidity index score, and well-known predisposing factors for NTS, including autoimmune diseases, acquired immunodeficiency syndrome, di

SUBMITTER: Wu HH 

PROVIDER: S-EPMC4650768 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature