Metabolic Characterization of the Common Marmoset (Callithrix jacchus).

ABSTRACT: High-resolution metabolomics has created opportunity to integrate nutrition and metabolism into genetic studies to improve understanding of the diverse radiation of primate species. At present, however, there is very little information to help guide experimental design for study of wild populations. In a previous non-targeted metabolomics study of common marmosets (Callithrix jacchus), Rhesus macaques, humans, and four non-primate mammalian species, we found that essential amino acids (AA) and other central metabolites had interspecies variation similar to intraspecies variation while non-essential AA, environmental chemicals and catabolic waste products had greater interspecies variation. The present study was designed to test whether 55 plasma metabolites, including both nutritionally es

SUBMITTER: Go YM 

PROVIDER: S-EPMC4651467 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature