Age-Related Macular Degeneration and Incident Stroke: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in people over 65 years old in the United States and has been associated with cardiovascular risk and decreased survival. There is conflicting data, however, regarding the contribution of AMD to the prediction of stroke.

Aim

To determine whether AMD is a risk indicator for incident stroke in a meta-analysis of available prospective and retrospective cohort studies published in the English literature.

Methods

We performed a systematic literature search of all studies published in English with Pub Med and other databases from 1966 to August 2014, reporting stroke incidence in patients with macular degeneration. Two investigators independently extracted the data. A random

SUBMITTER: Fernandez AB 

PROVIDER: S-EPMC4651536 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature