Mediated and moderated effects of neurocognitive impairment on outcomes of treatment for substance dependence and major depression.

ABSTRACT:

Objective

Neurocognitive impairment has not consistently predicted substance use treatment outcomes but has been linked to proximal mediators of outcome. These indirect effects have not been examined in adults with substance dependence and co-occurring psychiatric disorders. We examined mediators and moderators of the effects of neurocognitive impairment on substance use among adults in treatment for alcohol or drug dependence and major depression (MDD).

Method

Participants were veterans (N = 197, mean age = 49.3 years, 90% male, 75% Caucasian) in a trial of 2 group interventions for alcohol/drug dependence and MDD. Measures examined here included intake neurocognitive assessments and percent days drinking (PDD), percent days using drugs (PDDRG), self-efficacy, 12-step affil

SUBMITTER: Worley MJ 

PROVIDER: S-EPMC4651969 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature