Nosocomial transmission of avian influenza A (H7N9) virus in China: epidemiological investigation.

ABSTRACT:

Study question

Can avian influenza A (H7N9) virus be transmitted between unrelated individuals in a hospital setting?

Methods

An epidemiological investigation looked at two patients who shared a hospital ward in February 2015, in Quzhou, Zhejiang Province, China. Samples from the patients, close contacts, and local environments were examined by real time reverse transcriptase (rRT) polymerase chain reaction (PCR) and viral culture. Haemagglutination inhibition and microneutralisation assays were used to detect specific antibodies to the viruses. Primary outcomes were clinical data, infection source tracing, phylogenetic tree analysis, and serological results.

Study answer and limitations

A 49 year old man (index patient) became ill seven days after visiting a live pou

SUBMITTER: Fang CF 

PROVIDER: S-EPMC4652199 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature