Ontology highlight
ABSTRACT:
SUBMITTER: Maksimovic J
PROVIDER: S-EPMC4652745 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Maksimovic Jovana J Gagnon-Bartsch Johann A JA Speed Terence P TP Oshlack Alicia A
Nucleic acids research 20150518 16
Due to their relatively low-cost per sample and broad, gene-centric coverage of CpGs across the human genome, Illumina's 450k arrays are widely used in large scale differential methylation studies. However, by their very nature, large studies are particularly susceptible to the effects of unwanted variation. The effects of unwanted variation have been extensively documented in gene expression array studies and numerous methods have been developed to mitigate these effects. However, there has bee ...[more]