Examining the Pathways Between Self-Awareness and Well-Being in Mild to Moderate Alzheimer Disease.

ABSTRACT:

Objective

To investigate the relationship between awareness of memory loss and psychological well-being in a nonclinically depressed sample of participants with mild to moderate Alzheimer disease (AD).

Methods

Study participants (N = 104) enrolled through Columbia University Medical Center and the University of Pennsylvania completed clinical and cognitive assessments. Participants were rated with regard to their degree of awareness of memory deficits and completed questionnaires relating to their psychological well-being, including mood and quality of life (QOL). Mediating models were used to establish the relationship between awareness, depression, and QOL and to examine potential mediators of awareness and depression, including psychological distress, objective memory def

SUBMITTER: Cines S 

PROVIDER: S-EPMC4653086 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature