The Subjective Experience of Pain: An FMRI Study of Percept-Related Models and Functional Connectivity.

ABSTRACT:

Objective

Previous work suggests that the perception of pain is subjective and dependent on individual differences in physiological, emotional, and cognitive states. Functional magnetic resonance imaging (FMRI) studies have used both stimulus-related (nociceptive properties) and percept-related (subjective experience of pain) models to identify the brain networks associated with pain. Our objective was to identify the network involved in processing subjective pain during cold stimuli.

Methods

The current FMRI study directly contrasted a stimulus-related model with a percept-related model during blocks of cold pain stimuli in healthy adults. Specifically, neuronal activation was modelled as a function of changes in stimulus intensity vs as a function of increasing/decreasing

SUBMITTER: Wilcox CE 

PROVIDER: S-EPMC4653099 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature