Autoimmune post-herpes simplex encephalitis of adults and teenagers.

ABSTRACT:

Objective

To report 14 patients with immune-mediated relapsing symptoms post-herpes simplex encephalitis (HSE) and to compare the clinical and immunologic features of the teenage and adult group with those of young children.

Methods

Prospective observational study of patients diagnosed between June 2013 and February 2015. Immunologic techniques have been reported previously.

Results

Among the teenage and adult group (8 patients, median age 40 years, range 13-69; 5 male), 3 had an acute symptom presentation suggesting a viral relapse, and 5 a presentation contiguous with HSE suggesting a recrudescence of previous deficits. Seven patients developed severe psychiatric/behavioral symptoms disrupting all social interactions, and one refractory status epilepticus. Blepharos

SUBMITTER: Armangue T 

PROVIDER: S-EPMC4653102 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature