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Plasma proteomic analysis of active and torpid greater mouse-eared bats (Myotis myotis).


ABSTRACT: Hibernation is a physiological adaptation to overcome extreme environmental conditions. It is characterized by prolonged periods of torpor interrupted by temporary arousals during winter. During torpor, body functions are suppressed and restored rapidly to almost pre-hibernation levels during arousal. Although molecular studies have been performed on hibernating rodents and bears, it is unclear how generalizable the results are among hibernating species with different physiology such as bats. As targeted blood proteomic analysis are lacking in small hibernators, we investigated the general plasma proteomic profile of European Myotis myotis and hibernation associated changes between torpid and active individuals by two-dimensional gel electrophoresis. Results revealed an alternation of prot

SUBMITTER: Hecht AM 

PROVIDER: S-EPMC4653738 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature