Improve the prevention of sudden cardiac arrest in emerging countries: the Improve SCA clinical study design.

ABSTRACT:

Aims

This study aims to demonstrate that primary prevention (PP) patients with one or more additional risk factors are at a similar risk of life-threatening ventricular arrhythmias when compared with secondary prevention (SP) patients, and would receive similar benefit from an implantable cardioverter defibrillator (ICD), or cardiac resynchronization therapy-defibrillator (CRT-D) implant. The study evaluates the benefits of therapy for high-risk patients in countries where defibrillation therapy for PP of SCA is underutilized.

Methods

Enrolment will consist of 4800 ICD-eligible patients from Asia, Latin America, Eastern Europe, the Middle East, and Africa. Upon enrolment, patients will be categorized as SP or PP. Primary prevention patients will be assessed for additional ri

SUBMITTER: Zhang S 

PROVIDER: S-EPMC4654425 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature